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那库巴坦

那库巴坦

CAS号 1452458-86-4
规格 1g/包,10g/包
纯度 ≥98%
货号 WTM-06-00
货期 ---
品牌 唯特医药科技
库存 20g
注意:请务必与卖家联系核实单价库存,以确保您的资金安全及交易顺利。
参考价: ¥15000.00 元/克
货号 品牌 纯度 规格 参考价 货期
WTM-06-00 唯特医药科技 ≥98% 1g/包,10g/包 ¥15000.00元/克 ---

产品详情

详细信息(中文):
Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and class C β-lactamases. Nacubactam (OP0595 free acid) acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs.
详细信息(英文):
Nacubactam is a Phase 3-ready beta-lactamase inhibitor which works through multiple mechanisms of action, inhibiting a number of beta-lactamase enzymes as well as certain bacterial cell wall enzymes, lending the candidate a broad spectrum of activity when used in combination with beta-lactam antibiotics. In non-clinical studies, nacubactam-meropenem was shown to have potent antimicrobial activity against complicated urinary tract and severe respiratory tract infections, including those caused by meropenem-resistant strains, and against infections caused by CRE. In previously reported Phase 1 clinical studies, it was demonstrated that intravenous nacubactam was well tolerated among healthy volunteers when administered alone or in combination with meropenem. In these studies, nacubactam had no effect on ECG or vital signs parameters, and no trends in laboratory tests were observed. Pharmacokinetic studies in renal impaired patients and in cUTI patients have also been completed.

产品实物图

产品实物图

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英文名 ---
中文名 ---
CAS号 溶解性 ---
分子量 --- 熔点 ---
密度 --- 沸点 ---

商家信息

河北唯特医药科技有限公司

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号码一: 131****

号码二: 135****

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  • 公司类型:研发型
  • 成立时间:2020-05-28
  • 所在地区:河北省石家庄市
  • 注册资本:300万元
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