欢迎来到化学加!萃聚英才,共享化学!化学加,加您更精彩!客服热线:400-8383-509

化学加_合成化学产业资源聚合服务平台

020-29116152

(工作日8:30-18:00)

图片加载中
LOADING IMAGES
3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4- carboxamide

3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4- carboxamide

CAS号 1197300-24-5
规格 5mg10mg
纯度 98%
货号 HY-14229
货期 3天
品牌 Medchemexpress
库存 ---
注意:请务必与卖家联系核实单价库存,以确保您的资金安全及交易顺利。
参考价: ¥2604.00 元/5mg
货号 品牌 纯度 规格 参考价 货期
HY-14229 Medchemexpress 98% 5mg10mg ¥2604.00元/5mg 3天

产品详情

详细信息(中文):
TGR5 Receptor Agonist是TGR5(GPCR19)激动剂。
详细信息(英文):
产品描述:TGR5 Receptor AgonistTGR5 Receptor Agonist, a potent TGR5(GPCR19) agonist, showed improved potency in the U2-OS cell assay (pEC50 = 6.8) and in melanophore cells (pEC50 = 7.5)._x000D_ IC50 value: 6.8 (pEC50, U2-OS cell assay); 7.5(pEC50, melanophore cell) [1]_x000D_ Target: TGR5_x000D_ TGR5 Receptor Agonist was profiled against more than 100 in-house and external 7TM, ion channel, enzyme, transporter, and nuclear hormone receptor selectivity assays, including FXR, another bile acid receptor, and showed significant response only in secretion of the pro-inflammatory cytokine TNFalpha (pIC50 = 6.8) in human primary monocytes following stimulation with LPS (lipopolysaccharide). In addition, TGR5 Receptor Agonist has good physicochemical properties and no measurable activity against three of the common cytochrome P450 (CYP450) isoforms (1A2, 2C9, and 2D6) or hERG dofetilide binding (pIC50

产品百科查看更多

英文名 3-(2-Chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-1,2-oxazole-4- carboxamide
中文名 3-(2-氯苯基)-n-(4-氯苯基)-n,5-二甲基-4-异噁唑羧酰胺
CAS号 1197300-24-5 溶解性 ---
分子量 361.22200 熔点 ---
密度 --- 沸点 ---

商家信息

上海皓元生物医药科技有限公司

营业执照已审核 企业已认证

联系人:皓元 点击这里给我发消息

号码一: 400****

号码二: 021****

VIP企业默认展示联系方式,非VIP企业仅限注册登录用户可见

  • 公司类型:研发型
  • 成立时间:2009-03-17
  • 所在地区:上海市市辖区
  • 注册资本:300万元
推荐供应商

产品:3-(2-氯苯基)-n-(4-氯苯基)-n,5-二甲基-4-异噁唑羧酰胺