十六酰胺乙醇 CAS#:544-31-0_无锡西玛生物科技有限公司

LOADING IMAGES

十六酰胺乙醇

CAS号	544-31-0
规格	25KG桶	纯度	98%
货号	CS-PEA	货期	现货
品牌	Cima	库存	10000kg
规格	25KG桶
纯度	98%
货号	CS-PEA
货期	现货
品牌	Cima
库存	10000kg
注意：请务必与卖家联系核实单价库存，以确保您的资金安全及交易顺利。
参考价：￥10.00 元/公斤

立即询盘

货号	品牌	纯度	规格	参考价	货期
CS-PEA	Cima	98%	25KG桶	￥10.00元/公斤	现货

产品详情

详细信息(中文)：
什么是十六酰胺乙醇（PEA）？
CAS 号: 544-31-0
名称：十六酰胺乙醇
别名：(HYDROXYETHYL)PALMITAMIDE;
PALMITOYLETHANOLAMIDE;
十六酰胺乙醇（PEA）是一种内源性脂肪酸酰胺，属于类的核因子激动剂。 PEA已被证明结合在细胞核受体（核受体）和施加一个很大的各种相关的慢性疼痛和炎症的生物学功能。主要目标被认为是过氧化物酶体增殖物激活受体α（PPAR-α）。 PEA也具有亲和性大麻素样G偶联受体GPR55和GPR119.PEA不能严格被认为是一个经典大麻素，因为它缺乏亲和性的大麻素受体CB1和CB2。然而，PEA的存在下（和其它结构上相关的N- acylethanolamines）已被公知的由一个所谓的“随从效应”，以加强anandamide的活性。

十六酰胺乙醇（PEA）的来源
十六酰胺乙醇是在动物，海洋和植物来源的许多不同细胞中发现的一种天然存在的脂质。1954 年，Coburn et al（柯本），首先从大豆卵磷脂，蛋黄和花生粉中分离出来。自从 1933年诺贝尔经济学奖得主莱维-蒙塔尔奇尼的论文展示 PEA 抑制肥大细胞的重要效果以来，PEA越来越受到人们的重视。1970 年，捷克斯洛伐克医药企业 Spofa 推出以 500mgPEA 为有效成分的 Impulsin，用以治疗流感和呼吸道感染的预防。1975 年，捷克医生用 1.8g/天的 PEA 和 3g/天的阿司匹林作对照，比较其在减缓关节疼痛作用中的结果，发现都具有减轻疼痛和增强关节运动的作用。1976 年，西班牙企业 ALMIRALL 引入十六酰胺乙醇悬浮液和片剂作为新剂型在市场上推广。20 世纪 90 年代，在 PEA 的基础上，科学家们更深入的了解了内源脂肪酸衍生物的功能，例如油酰乙醇胺 OEA，十八酰胺乙醇 SEA 等，某些物质如花生四烯酸乙醇胺具有和 PEA 类似的功效和机理，在疼痛和镇痛模型上具有一定程度的协同作用。

十六酰胺乙醇（PEA）的主要功能
具有抗炎，抗感受伤害，神经保护，减轻慢性疼痛和抗惊厥作用。

临床意义：
人们一直尝试探究临床中 PEA 对各种神经性疼痛和慢性疼痛的作用，其效果基本都与 PPAR-α受体被激活相关，比如糖尿病性神经痛，坐骨神经痛，疼痛综合征，骨盆疼痛和压迫性神经性疼痛，并成功通过了安慰剂实验，这表明 PEA 在髓纤维组织中确实发挥了积极和期望的作用，自 2012 年起，人们发现了一些新的功效，包括青光眼的预防和恢复。在临床中 PEA 剂型主要有 400mg 胶囊，300mg 和 600mg 片剂，还有 0.3%和 1.5%的乳膏

建议用量
正常情况下每日1200mg，特殊情况可适当增减。

为什么选择西玛十六酰胺乙醇（PEA）？
1、含量高（98%）
2、无特殊异味
3、大规模生产，有库存
4、发货速度快
5、种类齐全（普通型、微米化、片剂、胶囊等）

详细信息(英文)：
What is Palmitoyl Ethanolamide?
CAS Number：544-31-0
Product Name：Palmitoyl Ethanolamide
Other Name：(HYDROXYETHYL)PALMITAMIDE;
2-(PALMITOYLAMINO)ETHANOL;
2-PALMITAMIDOETHANOL;
AM3112;
IMPULSIN;
LORAMINEP256;
N-(2-HYDROXYETHYL)HEXADECANAMIDE;
N-(2-HYDROXYETHYL)PALMITAMIDE;
N-HEXADECANOYLETHANOLAMINE;
N-PALMITOYLETHANOLAMINE;
NSC23320;
PALMIDROL;
PALMITICACIDMONOETHANOLAMIDE;
PALMITICMONOETHANOLAMIDE;
PALMITOYLETHANOLAMIDE;
Palmitoylethanolamide, is relatively new to most customers, and is sold first as a medicine in Netherlands under the trademark of PEAPURE for the treatment of Nerve Pain or Migraine. However, palmitoyl ethanolamide is now popularly marketed in the United States and Europe as a dietary supplement ingredient in the formulas of sports nutrition for joint support, pain release, etc.
According to Wikipedia, Palmitoyl ethanolamide (PEA), an endocannabinoid, belongs to a family of endogenous (body-own) lipid amides. It is secreted by human adipocytes and possesses anti-inflammatory, analgesic, possibly vasomodulation properties, a significant antiepileptic effect and may be used in treatment of anxiety disorders and anti-depression.
Since 2012 it is also available in the USA and it is shipped to the USA via the Netherlands. Meanwhile there are many hundreds of satisfied US citizens using this natural painkiller.

Development of Palmitoyl Ethanolamide
Since 2008, Palmitoyl Ethanolamide has been marketed as a food for special medical purposes in Italy and Spain, under the brand name Nor mast (Epitech Srl). Recently, a food-supplement named PeaPure was introduced (JP Russell Science Ltd.). In the USA, Palmitoyl Ethanolamide is under evaluation as a nutraceutical for inflammatory bowel syndrome (proposed brand name Recoclix, CM&D Pharma Ltd.; Nestlé).
Since 2014 there is also available a new Palmitoyl Ethanolamide cream, to enhance the effects of Palmitoyl Ethanolamide(PEA) also via the thin nerves in the skin.

Origin and occurrence of Palmitoyl Ethanolamide
PEA, also called N-Palmitoylethanolamide or palmidrol by some authors, is a naturally occurring C16:0 fatty acid derivative where the carboxylate function is amidated by the primary amine of ethanolamine. Its chemical name is N-(2-hydroxyethyl)hexadecanamide. PEA was first synthesized by refluxing ethanolamine with palmitic acid giving white crystals melting at 98-99°C.
The evidence that PEA is a natural compound came from Kuehl et al. who isolated PEA from soybean lecithin, egg yolk and peanut meal. In 1965 Bachur and co-workers

Benefits of taking Palmitoyl Ethanolamide supplements
Palmitoy Ethanolamide has been shown to have anti-inflammatory, anti-nociceptive, neuroprotective, and anticonvulsant properties. And many sports nutrition supplements are starting to use it in formulas of joint supports, brain health, together with natural products like Cissus Quadrangularis, SAMe, MSM, glucosamine, chondroitin,etc.

Chronic Pain
A Wikipedia article suggests PEA may be most effective in chronic pain disorders such as peripheral neuropathy, chronic regional pain syndrome (CRPS), sciatica, and nerve entrapment. A recent study suggests it could be helpful in Fibromyalgia.
For many weightlifters and bodybuilders this is their joints. Tendons and ligaments bear the brunt of punishing weight-lifting sessions, commonly becoming inflamed and sore.
The connective tissue just can’t keep up with the heavier and heavier weights lifted week after week.
Niggling pains become chronic injuries, often requiring a forced rest, a change of routine or the permanent dropping of some exercises altogether.
Hesselink reports that clinical trials involving over 6,000 people have established PEA’s effectiveness in treating chronic pain and inflammation. Animal models suggest PEA is able to prevent or inhibit two key processes in production of chronic nerve pain: nerve sprouting and dorsal root ganglia activation. cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). Why is PEA not better known in the West? PEA appears to been used in Italy and Spain for quite some time. Interest picked up in the Netherlands and Germany when a Netherlands distributor came on the scene. It’s hardly known in the U.S., although Palmitoyl Ethanolamide For Pain reports that “many people” on the West coast of the U.S. as well as Australia and Canada are using it.

Side effects of Palmitoyl Ethanolamide
Since Palmitoyl Ethanolamide is an endogenous fatty acid, and there is no any troublesome adverse effects and easy to use to reduce pain, even together with other drugs. There are no known significant adverse effects about Palmitoyl Ethanolamide have been reported.

Palmitoyl Ethanolamide dosage
Palmitoyl Ethanolamide is available as capsules of 400 mg (step in dose: take 1200 mg daily).

Our advantage
1.Higher Content(98%）
2. No special smell
3. Mass production and in stock
4. Micronized powder and an easy absorption.
5. Full range(ordinary, Micron, tablets, capsules, etc)

Where to buy Palmitoyl Ethanolamide?
Bulk Palmitoyl Ethanolamide is under mass production from Wuxi Cima science Co., Ltd. All information regarding specifications, certificate of analysis (COA), MSDS, and pricing for Palmitoyl Ethanolamide is available. Our aim is to offer the best quality PEA ingredient for sports nutrition industry.

产品实物图

产品百科查看更多

物理化学性质
英文名	palmitoyl ethanolamide
中文名	十六酰胺乙醇
CAS号	544-31-0	溶解性	---
分子量	299.49200	熔点	---
密度	0.91 g/cm3	沸点	461.5ºC at 760 mmHg

商家信息

无锡西玛生物科技有限公司

联系人：陈经理

号码一： 188****

号码二： 188****

VIP企业默认展示联系方式，非VIP企业仅限注册登录用户可见

公司类型：研发型
成立时间：2010-03-13
所在地区：江苏省无锡市
注册资本：180万元

进入店铺

推荐供应商

产品：十六酰胺乙醇

查看全部供应商

手机号绑定

请输入校验码

请选择用户类型

绑定企业