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扑尔敏扑尔敏扑尔敏扑尔敏 扑尔敏

扑尔敏

CAS号 113-92-8
规格 25kg/纸板桶(根据客户要求包装)
纯度 99%
货号 39086
货期 3天
品牌 艾宁泰
库存 680kg
注意:请务必与卖家联系核实单价库存,以确保您的资金安全及交易顺利。
参考价: ¥1.00 元/公斤
货号 品牌 纯度 规格 参考价 货期
39086 艾宁泰 99% 25kg/纸板桶(根据客户要求包装) ¥1.00元/公斤 3天

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详细信息(中文):
扑尔敏

中文别名:马来那敏;扑尔敏; 马来酸氯苯吡胺; 氯屈米通; 马来酸氯苯那敏;
英文名称:Chlorphenamine Maleate
英文别名:chlorphenamine hydrogen maleate
CAS 号:113-92-8
化学名:N,N-二甲基-γ-(4-氯苯基)-2-吡啶丙胺顺丁烯二酸盐
分 子 式:C20H23ClN2O4
分子量:390.86
含量:99%
熔点:130-135 °C(lit.)
储存条件:-20°C Freezer
水溶解性:1-5 g/100 mL at 21 ºC
类别:抗变态反应用药

化学性质:白色结晶性粉末。熔点131-135℃。易溶于水、乙醇、氯仿,微溶于乙醚、无臭、味苦。
包装:25公斤/桶。
用途:用作抗过敏药
用途:该品抗组织胺作用超过苯海拉明和异丙嗪,用量小,副作用轻。用于荨麻疹、血管舒张性鼻炎、感冒、哮喘、鼻炎、接触性皮炎,也用于药物和食物等引起的过敏症、虫咬及晕动等。
用途:抗组织胺药。与氯屈米通相类似,溴苯吡胺也中抗组织胺药。溴苯吡胺的生产方法也与氯屈米通相类似,只不过将起始原料用溴苯化合物代替。

生产方法:由2-对氯苄基吡啶经两步缩合而得。在干燥的反应锅内,加入氨钠、无水甲苯,加热至回流,将2-对氯苄基吡啶和溴代乙醛缩二乙醇同时滴入。加毕,回流反应8h。冷却静置,取甲苯液,固体物用少量水溶解后以甲苯提取。将提取液与甲苯液合并,水洗至中性,回收甲苯,得3-对氯苯-3-(2-吡啶基)-丙醛缩二乙醇。将其与DMF混匀加入反应锅,搅拌下加入甲酸与水的混合液。加热至110-120℃反应2h,150-160℃反应3h。冷却,减压回收DMF,加热水稀释,用碱液调至pH14。然后用甲苯提取,用水洗提取液至中性,回收甲苯后减压蒸馏,收集150-190℃馏分,得氯屈米通。

详细信息(英文):
chlorpheniramine

Chinese alias: melamine; chlorpheniramine; chlorpheniramine maleate; chlorhexidine; chlorpheniramine maleate;
English name: Chlorphenamine Maleate
English alias: chlorphenamine hydrogen maleate
CAS Number: 113-92-8
Chemical name: N,N-dimethyl-γ-(4-chlorophenyl)-2-pyridinepropylamine maleate
Molecular Formula: C20H23ClN2O4
Molecular weight: 390.86
Content: 99%
Melting point: 130-135 °C (lit.)
Storage condition: -20°C Freezer
Water solubility: 1-5 g/100 mL at 21 oC
Category: Anti-allergy medication

Chemical properties: White crystalline powder. 131-135°C. Soluble in water, ethanol, chloroform, slightly soluble in ether, odorless, bitter taste.
Packing: 25 kg/barrel.
Uses: Used as anti-allergic drugs
Uses: The product anti-histamine effect than diphenhydramine and promethazine, the amount of small, side effects are light. For urticaria, vasodilator rhinitis, colds, asthma, rhinitis, contact dermatitis, but also for allergies caused by drugs and food, insect bites and motion sickness.
Uses: Antihistamines. Similar to chlorhexidine, bromophenylamine is also an antihistamine. Bromopyramide is also produced in a similar manner as chlorotrimetrazine, except that the starting material is replaced by a bromobenzene compound.

Production methods : from 2-chlorobenzyl pyridine derived by two-step condensation. In a dry reaction vessel, ammoniacal sodium and anhydrous toluene were added, heated to reflux, and 2-p-chlorobenzylpyridine and bromoacetaldehyde diethyl acetal were simultaneously added dropwise. After the addition, reflux reaction 8h. After cooling, the toluene solution was taken and the solid matter was dissolved in a small amount of water and extracted with toluene. The extract was combined with toluene, washed with water to neutrality, and toluene was recovered to give 3-p-chlorobenzene-3-(2-pyridyl)-propionaldehyde diethyl acetal. Mix it with DMF and add it to the reaction pot. Add a mixture of formic acid and water under stirring. The reaction w

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英文名 Chlorpheniramine maleate
中文名 扑尔敏
CAS号 113-92-8 溶解性 1-5 G/100 ML AT 21 ºC
分子量 390.86100 熔点 130-135 °C(lit.)
密度 1.107 g/cm3 沸点 379ºC at 760 mmHg

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  • 公司类型:贸易商
  • 成立时间:2017-05-23
  • 所在地区:广东省深圳市
  • 注册资本:50万元
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