penicillamine CAS#:52-66-4_上海陶素生化科技有限公司

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penicillamine

CAS号	52-66-4
规格	5 mgmg/瓶	纯度	99.0%
货号	T0983L	货期	现货
品牌	TargetMol	库存	需咨询
规格	5 mgmg/瓶
纯度	99.0%
货号	T0983L
货期	现货
品牌	TargetMol
库存	---
注意：请务必与卖家联系核实单价库存，以确保您的资金安全及交易顺利。
参考价：￥192.00 元/瓶

立即询盘

货号	品牌	纯度	规格	参考价	货期
T0983L	TargetMol	99.0%	5 mgmg/瓶	￥192.00元/瓶	现货
T0983L-5 mg	TargetMol	98%	5毫克/瓶	￥192.00元/瓶	一个工作日
T0983L-50 mg	TargetMol	98%	50毫克/瓶	￥1064.00元/瓶	一个工作日
T0983L-200 mg	TargetMol	98%	200毫克/瓶	￥1952.00元/瓶	一个工作日
T0983L-10 mg	TargetMol	98%	10毫克/瓶	￥336.00元/瓶	一个工作日
T0983L-25 mg	TargetMol	98%	25毫克/瓶	￥664.00元/瓶	一个工作日
T0983L-100 mg	TargetMol	98%	100毫克/瓶	￥1383.00元/瓶	一个工作日

详细信息(英文)：
DL-Penicillamine is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. DL-Penicillamine is only found in individuals that have used or taken this drug. It is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease. From in vitro studies which indicate that one atom of copper combines with two molecules of DL-penicillamine. DL-Penicillamine also reduces excess cystine excretion in cystinuria. This is done, at least in part, by disulfide interchange between DL-penicillamine and cystine, resulting in the formation of penicillamine-cysteine disulfide, a substance that is much more soluble than cysteine and is excreted readily. DL-Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. The mechanism of action of DL-penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. Unlike cytotoxic immunosuppressants, DL-penicillamine markedly lowers IgM rheumatoid factor but produces no significant depression in absolute levels of serum immunoglobulins. Also unlike cytotoxic immunosuppressants which act on both, DL-penicillamine in vitro depresses T-cell activity but not B-cell activity.