Lesinurad sodium CAS#:1151516-14-1_上海皓元生物医药科技有限公司

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Lesinurad sodium

CAS号	1151516-14-1
规格	5mg10mg	纯度	98%
货号	HY-15258A	货期	3天
品牌	Medchemexpress	库存	需咨询
规格	5mg10mg
纯度	98%
货号	HY-15258A
货期	3天
品牌	Medchemexpress
库存	---
注意：请务必与卖家联系核实单价库存，以确保您的资金安全及交易顺利。
参考价：￥550.00 元/5mg

立即询盘

货号	品牌	纯度	规格	参考价	货期
HY-15258A	Medchemexpress	98%	5mg10mg	￥550.00元/5mg	3天

产品详情

详细信息(中文)：
Lesinurad sodium (RDEA594 sodium)是URAT1抑制剂。

详细信息(英文)：
产品描述：Lesinurad (sodium)Lesinurad sodium (RDEA594 sodium) is an once-daily inhibitor of URAT1; URAT1 is a transporter in the kidney that regulates uric acid excretion from the body._x000D_ IC50 Value:_x000D_ Target: URAT1_x000D_ in vitro:_x000D_ in vivo: In healthy subjects, the combination of 40 mg FBX with RDEA-594 reduced sUA by approximately 70% at the 200 mg and 400 mg RDEA-594 dose levels, respectively. In gout patients, FBX 40 mg and 80 mg alone reduced sUA by 35% and 47%, respectively. FBX 40 mg + RDEA-594 reduced sUA by 56% and 61% when combined with RDEA-594 400 mg or 600 mg. respectively, resulting in response rates of 100% for sUA